Medchembench

    ๐Ÿ† Leaderboard

    As of August 31, 2026, GPT-5.6 Sol is #1 for Medchembench at 48.3%. Ranked by the Medchembench score 3 models in this index have a published Medchembench score. Medchembench leaderboard: rank models by Medchembench next to live API token prices.

    Updated August 31, 2026345 models36 providers
    GPT-5.6 Sol
    OpenAI ยท Proprietary
    48.3%$35.00
    GPT-5.6 Terra
    OpenAI ยท Proprietary
    35%$14.00
    GPT-5.6 Luna
    OpenAI ยท Proprietary
    30.4%$1.40
    ChatGPT-4o Latest
    OpenAI ยท Proprietary
    โ€”$12.50
    Claude 3 Haiku
    Anthropic ยท Proprietary
    โ€”$1.50
    Claude 3 Opus
    Anthropic ยท Proprietary
    โ€”$90.00
    Claude 3 Sonnet
    Anthropic ยท Proprietary
    โ€”$18.00
    Claude 3.5 Haiku
    Anthropic ยท Proprietary
    โ€”$4.80
    Claude 3.5 Sonnet
    Anthropic ยท Proprietary
    โ€”$18.00
    Claude 3.5 Sonnet
    Anthropic ยท Proprietary
    โ€”$18.00
    Claude 3.7 Sonnet
    Anthropic ยท Proprietary
    โ€”$18.00
    Claude Fable 5
    Anthropic ยท Proprietary
    โ€”$60.00
    Claude Haiku 4.5
    Anthropic ยท Proprietary
    โ€”$6.00
    Claude Mythos 5
    Anthropic ยท Proprietary
    โ€”$60.00
    Claude Mythos Preview
    Anthropic ยท Proprietary
    โ€”$60.00
    Claude Opus 4
    Anthropic ยท Proprietary
    โ€”$90.00
    Claude Opus 4.1
    Anthropic ยท Proprietary
    โ€”$90.00
    Claude Opus 4.5
    Anthropic ยท Proprietary
    โ€”$30.00
    Claude Opus 4.6
    Anthropic ยท Proprietary
    โ€”$30.00
    Claude Opus 4.7
    Anthropic ยท Proprietary
    โ€”$30.00
    Claude Opus 4.8
    Anthropic ยท Proprietary
    โ€”$30.00
    Claude Opus 5
    Anthropic ยท Proprietary
    โ€”$30.00
    Claude Sonnet 4
    Anthropic ยท Proprietary
    โ€”$18.00
    Claude Sonnet 4.5
    Anthropic ยท Proprietary
    โ€”$18.00
    Claude Sonnet 4.6
    Anthropic ยท Proprietary
    โ€”$18.00
    Claude Sonnet 5
    Anthropic ยท Proprietary
    โ€”$12.00
    Codestral-22BOSS
    Mistral ยท Open Source ยท via Mistral AI
    โ€”$1.20
    Command A+OSS
    Cohere ยท Open Source
    โ€”$12.50
    Command R+OSS
    Cohere ยท Open Source
    โ€”$1.25
    Composer 2
    Cursor ยท Proprietary
    โ€”$3.00
    Composer 2 Fast
    Cursor ยท Proprietary
    โ€”$9.00
    DeepSeek R1 Distill Llama 70BOSS
    DeepSeek ยท Open Source
    โ€”$0.50
    DeepSeek R1 Distill Qwen 32BOSS
    DeepSeek ยท Open Source
    โ€”$0.30
    DeepSeek VL2OSS
    DeepSeek ยท Open Source ยท via Replicate
    โ€”$2.80
    DeepSeek VL2 SmallOSS
    DeepSeek ยท Open Source ยท via Replicate
    โ€”$1.70
    DeepSeek VL2 TinyOSS
    DeepSeek ยท Open Source ยท via Replicate
    โ€”$0.90
    DeepSeek-R1OSS
    DeepSeek ยท Open Source
    โ€”$2.74
    DeepSeek-R1-0528OSS
    DeepSeek ยท Open Source
    โ€”$2.74
    DeepSeek-V2.5OSS
    DeepSeek ยท Open Source
    โ€”$0.42
    DeepSeek-V3OSS
    DeepSeek ยท Open Source
    โ€”$1.37
    DeepSeek-V3 0324OSS
    DeepSeek ยท Open Source
    โ€”$1.42
    DeepSeek-V3.1OSS
    DeepSeek ยท Open Source
    โ€”$1.27
    DeepSeek-V3.2OSS
    DeepSeek ยท Open Source ยท via OpenRouter
    โ€”$0.57
    DeepSeek-V3.2 (Non-thinking)OSS
    DeepSeek ยท Open Source
    โ€”$0.70
    DeepSeek-V3.2-ExpOSS
    DeepSeek ยท Open Source
    โ€”$0.68
    DeepSeek-V4-Flash-0423OSS
    DeepSeek ยท Open Source
    โ€”$0.30
    DeepSeek-V4-Flash-0731OSS
    DeepSeek ยท Open Source
    โ€”$1.76
    DeepSeek-V4-Flash-MaxOSS
    DeepSeek ยท Open Source
    โ€”$0.42
    DeepSeek-V4-Flash-Vision-Exp
    DeepSeek ยท Proprietary
    โ€”$0.88
    DeepSeek-V4-Pro-0813OSS
    DeepSeek ยท Open Source
    โ€”$5.28
    Showing 1โ€“50 of 345 models

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    The index

    All Large Language Models

    345 models across 36 providers. Search or jump to a lab โ€” every model page stays linked here.

    Baidu

    2 models

    Inception

    1 models

    inclusionAI

    1 models

    LG AI Research

    1 models

    Liquid AI

    2 models

    Nous Research

    1 models

    OpenBMB

    1 models

    Sakana AI

    1 models

    Sarvam AI

    2 models

    Tencent

    1 models

    Thinking Machines

    1 models

    Unisound

    1 models

    Upstage

    1 models

    Which model leads Medchembench right now?

    As of August 31, 2026, GPT-5.6 Sol by OpenAI is #1 for Medchembench at 48.3%. Ranked by the Medchembench score This board also tracks Medchembench. Next on the same board: GPT-5.6 Terra and GPT-5.6 Luna. This medchembench leaderboard ranks models by Medchembench. Scores come from public evals. Prices are the live API rates in the table above.

    Sources: OpenAI API pricing (https://developers.openai.com/api/docs/pricing); Anthropic Claude API pricing (https://platform.claude.com/docs/en/about-claude/pricing); Gemini API pricing (https://ai.google.dev/gemini-api/docs/pricing)

    Top 3 for medchembench. Ranked by the Medchembench score Input and output are dollars per million tokens.
    RankModelMedchembenchInput /MOutput /M
    1GPT-5.6 Sol48.3%$5.00$30.00
    2GPT-5.6 Terra35%$2.00$12.00
    3GPT-5.6 Luna30.4%$0.20$1.20

    Medchembench FAQ

    Who ranks #1 on the Medchembench leaderboard?

    As of August 31, 2026, GPT-5.6 Sol by OpenAI ranks #1 on Medchembench at 48.3%. API pricing is $5.00/M input and $30.00/M output.

    What are the top models on Medchembench?

    The current Medchembench ranking as of August 31, 2026 is 1. GPT-5.6 Sol at 48.3%; 2. GPT-5.6 Terra at 35%; 3. GPT-5.6 Luna at 30.4%.

    Which medchembench model is the cheapest?

    GPT-5.6 Luna is the cheapest scored model on this medchembench leaderboard at $0.20/M input and $1.20/M output ($1.40 blended). GPT-5.6 Sol still leads Medchembench at 48.3%.

    Should I always pick the #1 Medchembench model?

    Not automatically. GPT-5.6 Sol leads Medchembench, but a cheaper scored model can be the better production choice if the quality gap is small. Use the table to weigh Medchembench against input/output price, context window, and related evals.

    How often is the Medchembench leaderboard updated?

    Scores and API prices on this page are refreshed from published evals and provider rates. The snapshot is labeled August 31, 2026. Treat it as a current index, not a one-off blog post.

    What is Medchembench?

    Medchembench is a public LLM eval (the Medchembench score). This page ranks models that have published a score, next to live API prices.

    Where is the Medchembench leaderboard?

    This page is the Medchembench leaderboard. Models are sorted by Medchembench, with input and output token prices on the same row so you can weigh score against cost. Official boards often omit price; that comparison is the point of this index.

    How is this Medchembench ranking different from the official board?

    Official eval pages own the methodology. This page keeps the published Medchembench score next to live API $/M so you can pick a production SKU, not only a trophy number.